Bladder Cancer Treatment

Bladder cancer is one of the most common cancers in the United States, affecting thousands of people every year. Early detection and advanced treatment options are key to successfully managing this condition. At Millennium Physicians, our dedicated team of specialists provides personalized care to ensure the best outcomes for our patients.

What is Bladder Cancer?

Bladder cancer begins when abnormal cells in the bladder start to grow uncontrollably. These cells can form tumors and may spread to other parts of the body if left untreated. Bladder cancer often causes symptoms such as blood in the urine, frequent urination, and discomfort during urination. Early detection plays a crucial role in the effective treatment of bladder cancer.

What Causes Bladder Cancer?

Bladder cancer occurs when the cells in the bladder begin to grow abnormally, forming tumors. While the exact cause isn’t always clear, several factors are known to increase the risk of developing bladder cancer. Smoking is one of the leading causes, as harmful chemicals in tobacco are absorbed into the bloodstream and filtered through the bladder, exposing its lining to carcinogens.

Other potential causes include prolonged exposure to industrial chemicals used in manufacturing, chronic bladder irritation from infections or catheter use, and a history of certain parasitic infections, such as schistosomiasis. Genetic mutations and a family history of bladder cancer can also play a role. Understanding these factors and taking steps to mitigate risks, like avoiding tobacco and reducing exposure to harmful substances, can help lower the likelihood of developing bladder cancer.

 

Risk Factors For Bladder Cancer

  • Smoking:The leading cause of bladder cancer, as tobacco chemicals accumulate in the bladder lining.
  • Chemical Exposure Prolonged exposure to industrial chemicals used in dyes, rubber, leather, and other manufacturing processes.
  • Age: The risk increases with age, with most cases occurring in people over 55.
  • Gender: Men are more likely to develop bladder cancer than women.
  • Chronic Bladder Irritation: Repeated bladder infections, long-term catheter use, or chronic inflammation.
  • Family History: A close relative with bladder cancer can increase your risk.
  • Personal History of Cancer: A history of bladder cancer or certain cancers in other areas can increase recurrence risk.
  • Radiation Therapy: Previous radiation treatment to the pelvic area may elevate risk.
  • Certain Medications: Long-term use of certain chemotherapy drugs, such as cyclophosphamide, or diabetes medication like pioglitazone.
  • Parasitic Infections: In regions where schistosomiasis is common, chronic bladder infections caused by this parasite can increase the risk.

Bladder Cancer Treatment Options

At Millennium Physicians, we provide a comprehensive range of advanced treatment options for bladder cancer, customized to meet each patient’s unique needs. Below are some of the most effective treatments available:

Surgery

Transurethral Resection of Bladder Tumor (TURBT):

  • Removes tumors from the bladder lining using a cystoscope.
  • Often used for early-stage bladder cancer.
  • Minimally invasive with no external incisions.

Radical Cystectomy:

  • Removes the entire bladder, and possibly nearby lymph nodes and surrounding organs.
  • Recommended for invasive or high-risk cancers.
  • May require reconstructive surgery to create a new way to store and pass urine.

Partial Cystectomy:

  • Removes only the cancerous portion of the bladder.
  • Preserves bladder function and is suitable for specific cases.

Intravesical Therapy

  • Delivers medication directly into the bladder via a catheter.
  • Often used for early-stage bladder cancer to prevent recurrence.
  • Includes treatments like Bacillus Calmette-Guérin (BCG) immunotherapy and chemotherapy drugs.

Chemotherapy

  • Uses drugs to kill cancer cells or prevent their growth.
  • Can be administered before surgery (neoadjuvant) or after surgery (adjuvant).
  • Sometimes used in combination with radiation therapy for advanced cases.

Immunotherapy

  • Boosts the body’s natural immune response to fight bladder cancer.
  • Drugs like immune checkpoint inhibitors are effective for advanced or metastatic cancers.

Radiation Therapy

  • Targets and destroys cancer cells with high-energy beams.
  • Often used to manage symptoms or as part of a combination treatment for advanced cancer.

Personalized Treatment Plans

Our multidisciplinary team works together to create personalized treatment plans that address the specific type and stage of your bladder cancer, as well as your overall health and personal preferences. At Millennium Physicians, we are committed to providing the most effective treatments and compassionate care for every patient.

Understanding and Managing Risk

Bladder cancer risk can be influenced by lifestyle, environmental, and genetic factors. Smoking is the leading cause of bladder cancer, as harmful chemicals from tobacco are absorbed into the bloodstream and eventually concentrated in the bladder. Prolonged exposure to industrial chemicals, especially those used in manufacturing dyes, rubber, and textiles, also significantly increases the risk. Chronic bladder irritation from infections, frequent catheter use, or conditions like schistosomiasis can contribute to bladder cell abnormalities, which may lead to cancer.

Managing bladder cancer risk begins with making informed lifestyle choices, such as quitting smoking and reducing exposure to harmful substances. Staying hydrated can also help flush out potential carcinogens from the bladder. For individuals with a family history of bladder cancer or other risk factors, regular screenings and consultations with a healthcare provider are essential. By understanding your personal risk and adopting proactive measures, you can take significant steps toward prevention and early detection. At Millennium Physicians, we provide guidance and support to help patients manage their risk and protect their health.

What is the Survival Rate of Bladder Cancer?

Generally, the five-year relative survival rate for all stages of bladder cancer combined is around 77%. However, this can vary significantly based on how early the cancer is detected:

  • Early-Stage (Localized): Higher survival rates (often above 90%) when the cancer is confined to the bladder.
  • Advanced (Metastatic): Lower survival rates if the cancer has spread to distant sites.

Factors such as the specific type of bladder cancer, overall health, and response to treatment also influence an individual’s outcome. Regular checkups and early detection remain key to improving survival odds. It’s always best to consult with a medical professional to receive personalized information about prognosis and treatment options.

Overall Survival Rates:

Urothelial Carcinoma (Transitional Cell Carcinoma)

The five-year relative survival rate for urothelial (transitional) cell carcinoma is approximately 77% for all stages combined, but this can vary significantly depending on the cancer’s stage at diagnosis and individual health factors.

Squamous Cell Carcinoma
Adenocarcinoma
Small Cell Carcinoma
Sarcomas

Types of Bladder Cancers We Treat

Urothelial Carcinoma (Transitional Cell Carcinoma)

This is the most common type, accounting for about 90% of all bladder cancer cases. It begins in the urothelial cells that line the inside of the bladder.

Squamous Cell Carcinoma

This type forms in the thin, flat cells that can develop in the bladder after long-term irritation or infection. It accounts for a small percentage of bladder cancers but can be more aggressive.

Adenocarcinoma

This rare form of bladder cancer starts in the cells of mucus-secreting glands and accounts for about 1-2% of bladder cancers.

Small Cell Carcinoma

A very rare and aggressive type of bladder cancer that starts in neuroendocrine cells (a type of nerve-related cell)

Sarcomas

These are extremely rare bladder cancers that start in the muscle cells of the bladder.

Frequently Asked Questions About Bladder Cancer

The most common symptom is blood in the urine (hematuria), which may be visible or detected through a urine test. Other symptoms include frequent urination, pain or burning during urination, and pelvic pain.